November 25, 2025
Image credit: Pixabay, Mohamed_hassan
11/20/2025
Research Article
Epaminondas Markos Valsamis and colleagues investigate the association between BMI, patient complications and implant survival after shoulder replacement surgery using linked national datasets from Denmark and the UK.
Image credit: Pixabay, XERO337
Browse Issues 2004 – 2025
12/01/2025
Perspective
In recognition of World AIDS Day 2025, this Perspective by Anthony Fauci and Gregory Folkers reflects on the progress made in antiretroviral treatments and prevention of HIV/AIDS, highlighting promising therapeutic developments and looking ahead to what is needed to end the AIDS epidemic.
Image credit: Unsplash, Ubaid E. Alyafizi
11/27/2025
Editorial
In this Editorial, Zulfiqar Bhutta discusses the Global Burden of Disease (GBD) 2023 report, outlining why, alongside improved health monitoring, data acquisition, and analytical methods, its continued expansion creates new challenges and opportunities for improving its accuracy, completeness, external validity, and policy relevance.
Image credit: Pixabay, AlLes
11/26/2025
Research Article
Jiaxin Xie, Xuesi Dong, Zilin Luo, and team use a multistate Markov model to quantify the long-term health and economic benefits of adhering to colorectal cancer screening, incorporating both traditional and biomarker-based initial screening methods.
Image credit: Xie J, Dong X, Luo Z, Wang C, Zheng Y, et al. (2025) The impact of adherence on colorectal cancer screening cost-effectiveness: A modeling study. PLOS Medicine
11/19/2025
Research Article
In this registry study, Jacques Wels and Natasia Hamarat use data on all cases of euthanasia in Belgium between 2002-2023 to assess trends in assisted dying for patients with psychiatric disorders and dementia.
Image credit: Pixabay, truthseeker08
11/20/2025
Perspective
This Perspective highlights exciting developments in preventative treatments and stem cell-based therapies for type 1 diabetes, discussing the prospects and hurdles of arresting or reversing the disease and achieving insulin independence for type 1 diabetics.
Image credit: Unsplash, isens usa
11/21/2025
Perspective
In this Perspective, Petra Heitkamp and colleagues highlight how international health aid cuts can present an opportunity to shift towards a more equitable, resilient, and self-reliant TB response.
Image credit: Unsplash, Aakash Dhage
11/05/2025
Research Article
By Lisanne van Prooyen Schuurman and colleagues.
Image credit: Natalie Bond, Pexels
11/06/2025
Perspective
This Perspective discusses how middle-income countries can prepare and succeed in transitioning away from external aid.
Image credit: Valentin Antonucci, Pexels
11/04/2025
Research Article
By Naomi R Waterlow and colleagues.
Image credit: CDC, Unsplash
In this Editorial, Guest Editors Timothy R. Walsh, Ana C. Gales, Ramanan Laxminarayan, and our PLOS Medicine Editor Philippa C. Dodd discuss the Special Issue dedicated to Antimicrobial resistance and emphasize the urgent threat of AMR.
Ruchita Balasubramanian and colleagues, estimate the incidence of hospital-associated infections resistant to antibiotics in 195 countries using point prevalence survey data.
James Neal Russell and colleagues explore antibiotic use and mortality prediction in hospitalised neonates and infants with sepsis.
Silvia Bertagnolio, Amitabh Bipin Suthar, Olga Tosas and Kitty Van Weezenbeek discuss surveillance of antimicrobial resistance, the existing limitations and the implications this has on accurate determination of incidence.
Yin Mo and colleagues investigate implications of antibiotic duration on antibiotic resistance in hospitals.
In this Special Issue, we present a fascinating array of research papers providing insights into various facets of mental health during the pandemic.
This collection of research articles highlights the multi-faceted challenges imposed by drug-resistant bacteria, the consequences for health and economics, and interventions that could lessen the burden.
In this Collection, PLOS Medicine presents high-quality translational research and clinical studies on advances in early cancer detection.
This Special Issue brings together the latest research on child and adolescent health, including strategies to monitor and combat child mortality from birth through adolescence, and environmental impacts on child health and mortality.
This 2019 Special Issue highlights the importance of nutrition for maternal and child health.
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